Publications

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Received 479+ citations, H-Index: 9

10) Kinetic comparison of 13 homogeneous thiol–X reactions (pdf)

Le-Thu T. Nguyen, M. Talha Gokmen, Filip E. Du Prez; Polym. Chem. 2013, 4, 5527-5536

A comprehensive on-line FTIR study of the reactivity of 14 substrates towards a thiol, including the effect of solvent and catalyst type and a comparison between thiol-X and amine-X reaction series. Supporting Information

9) Complexity from simplicity: unique polymer capsules, rods, monoliths, and liquid marbles prepared via HIPE in microfluidics (pdf)

M. Talha Gokmen, Busra Dereli, Bruno G. De Geest, Filip E. Du Prez*  Part Part Syst Char 2013, 30, 438-444

Porous polymer particles that are uniform in size and complex in shape such as capsules, rods and beads are prepared by using a simple tubing-needle based microfluidic setup. No complicated reactor design, sacrificial template, synthesized monomer or organic porogen are used; Monomers and water dictate the final shape. Beads self assemble into liquid marbles and capsules are reactive.

8) Chemically orthogonal trifunctional Janus beads by photochemical “sandwich” microcontact printing (pdf)

Chemically orthogonal trifunctional Janus beads by photochemical ?sandwich? microcontact printingTobias Kaufmann, Christian Wendeln, M. Talha Gokmen, Stefan Rinnen, Maria Becker, Heinrich F. Arlinghaus, Filip Du Prez* and Bart Jan Ravoo* Chemical Communications, 2013, 49, 63-65

The combination of topographic and chemical orthogonality on polymer particle surfaces by immobilization of functional thiols via thiol-ene chemistry provides a particle surface with azide and acid functionality on opposing sides. The resulting Janus beads are accessible for site selective orthogonal chemical reactions as well as biomolecular recognition on the same particle.

Supporting Information     Supporting Video   

 

7) Bifunctional Janus Beads Made by “Sandwich” Microcontact Printing and Click Chemistry (pdf)

Tobias Kaufmann, M. Talha Gokmen, Stefan Rinnen, Heinrich F. Arlinghaus, Filip E. Du Prez and Bart Jan Ravoo

Journal of Materials Chemistry201222, 6190-6199

“Sandwich” microcontact printing on beads is further explored. Next to epoxy-amine reaction, Cu (I) catalyzed azide-alkyne and thiol-yne additon (click) reactions were utilized. Patterned patches on beads is reported for the first time.  Moreover, the diameter of beads is reduced down to 5 micron.

Supporting Information 

 

6) Porous Polymer Particles – A Comprehensive Guide to Synthesis, Characterization, Functionalization and Applications (pdf)

M. Talha Gokmen, Filip E. Du Prez Progress in Polymer Science201237, 365-405 (citing 467 references)

This review is written to fulfill the need of a comprehensive guide for the manufacture of porous polymer particles. The extensive comparison of synthesis methods certainly makes this review also useful for the preparation of nonporous particles. The review is expected not only to enable individual experts of each field to compare their methods with the other ones, but also to be a handbook for the newcomers to this field to guide them from the synthesis to the applications.

 

5) Revealing the Nature of Thio-Click Reactions on the Solid Phase (pdf)

M. Talha Gokmen, Jérémy Brassinne, R. Arun Prasath and Filip E. Du Prez  

Chemical Communications201147, 4652-4654 

Thiol- and yne-functionalized beads were manufactured in a simple microfluidic setup. While CuAAC and thiol-yne reactions were performed on yne-functionalized beads, 9 different thiol-X reactions were compared, in terms of kinetics and conversion, on thiol-functionalized beads.

The paper was also mentioned in the Chem. Commun. Blog

Supporting Information 

4) “Sandwich” Microcontact Printing as a Mild Route Towards Monodisperse Janus Pariticles with Tailored Bifunctionality (pdf)

Tobias Kaufmann, M. Talha Gokmen, Christian Wendeln, Martin Schneiders, Stefan Rinnen, Heinrich F. Arlinghaus, Stefan A.F. Bon, Filip E. Du Prez, Bart J. Ravoo   Advanced Materials201123, 79-83

A monolayer of porous epoxy polymer microspheres is transformed into Janus particles with distinct functionality on each face by reaction with amine functional fluorescent dyes, carbohydrates, and magnetic nanoparticles.

 

3) Thiol-Ene and Thiol-Yne Chemistry in Microfluidics- A Straightforward Method Towards Macroporous and Nonporous Functional Polymer Beads (pdf)

R. Arun Prasath, M. Talha Gokmen, Pieter Espeel, Filip E. Du Prez   Polymer Chemistry20101, 685-692

Thiol-ene and thiol-yne reactions are explored as efficient pathways towards rapid production of diverse monodisperse macroporous and nonporous functional beads. 

 

 

2) Fabrication of Porous “Clickable” Polymer Beads and Rods through Generation of High Internal Phase (HIPE) Droplets in a Simple Microfluidic Device (pdf)

M. Talha Gokmen, Wim Van Camp, Patrick J. Colver, Stefan A. F. Bon and Filip E. Du Prez    Macromolecules 200942, 9289-9294

Water-in-oil high internal phase emulsion (HIPE) droplets were polymerized in microfluidics, resulting in “giga”porous beads and rods. These particles showed superior performance in a consecutive “click”-“click” modification.

Supporting information         Supporting Video

1) “Giant” Hollow Multilayer Capsules by Microfluidic Templating (pdf)

M. Talha Gokmen, Bruno G. De Geest, Wim E. Hennink and Filip E. Du Prez

ACS Applied & Mater. Interfaces 20091, 1196-1202

Monodisperse microgels were synthesized by a microfluidic setup and used as a sacrificial template for the fabrication of “giant” hollow polyelectrolyte capsules with rigid walls consisting of covalently cross-linked polyelectrolytes and metal nanoparticles.